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Paper I — 2025 March (Supplementary (SAY)) (2019 Scheme) — Qxii

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Paper I
2025 March (Supplementary (SAY)) (2019 Scheme) · 100 marks · 180 min

Question

Patient: Mrs. Rose, a 68-year-old woman, Chief Complaint: Gradual loss of vision in both eyes, particularly in the peripheral vision. Medical History: Hypertension, Type 2 Diabetes, and Hyperlipidaemia. No known drug allergies. Family History: Her father had glaucoma. Presenting Symptoms: Mrs. Rose reports difficulty seeing objects in her peripheral vision for the past 6 months. She has had a gradual decrease in her night vision as well. Ophthalmologic Exam: Intraocular pressure (IOP): 28 mmHg in both eyes Visual field: Decreased peripheral vision, with a loss in the superior field. Optic disc: Cupping noted in both eyes. Diagnosis: Open-angle glaucoma.

Mrs. Rose’s intraocular pressure (IOP) is 28 mmHg. Which class of drugs is most likely to lower IOP by decreasing aqueous humour production

  • a) Beta-blockers
  • c) Carbonic anhydrase inhibitors
  • b) Prostaglandin analogues
  • d) Alpha-2 adrenergic agonists (PTO)
Qxii1 marksMCQs (Case)

Answer

Correct answer: a) Beta-blockers

Beta-blockers (e.g. Timolol) lower IOP primarily by decreasing aqueous humour production at the ciliary epithelium.

  1. 1Adrenergic System

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