Paper I
2024 March (Supplementary) (2019 Scheme) · 100 marks · 180 min

Question

Prazosin/Phentolamine for the treatment of Benign hypertrophy of prostate (BPH) in elderly patients

Q130.2 marksShort Answers

Answer

Prazosin is the appropriate choice — an orally active alpha-1 blocker suitable for chronic, long-term use, relaxing bladder neck/prostatic smooth muscle to relieve obstructive urinary symptoms. Phentolamine is a short-acting, non-selective alpha blocker available only parenterally, used for acute settings (pheochromocytoma crisis, extravasation injury) — its short duration and non-selective action make it entirely unsuitable for the chronic oral management BPH requires.

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