Paper I
2022 October (Supplementary) (2010 Scheme) · 40 marks · 120 min

Question

Prazosin in Benign hypertrophy of prostate.

Q101 marksShort Answers

Answer

Prazosin is an alpha-1 blocker that relaxes smooth muscle in the bladder neck and prostatic capsule (rich in alpha-1A receptors), relieving the dynamic component of bladder outlet obstruction in benign prostatic hyperplasia and improving urinary flow, without shrinking the gland itself (unlike 5-alpha-reductase inhibitors, which reduce prostate size but act more slowly).

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