Paper I
2016 February (2010 Scheme) · 40 marks · 120 min

Question

Therapeutic uses of adrenergic drugs.

Q33 marksShort Notes

Answer

Adrenergic drugs (sympathomimetics) have wide clinical application based on their receptor selectivity:

  • Cardiogenic/septic shock: Dopamine, Dobutamine, Noradrenaline
  • Anaphylactic shock/severe allergic reaction: Adrenaline (drug of choice)
  • Cardiac arrest: Adrenaline
  • Hypotension: Noradrenaline, Phenylephrine
  • Bronchial asthma/COPD (bronchodilation): Salbutamol, Terbutaline (β2 agonists)
  • Nasal decongestion: Phenylephrine, Oxymetazoline (topical/local)
  • Prolongation of local anaesthetic action: Adrenaline (added to local anaesthetic solutions)
  • Attention-deficit hyperactivity disorder/narcolepsy: Amphetamine derivatives
  • Premature labour (tocolysis): Ritodrine, Isoxsuprine (β2 agonists)
  • Mydriasis (ophthalmic use): Phenylephrine

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