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Paper I — 2022 February (2019 Scheme) — Q10

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Paper I
2022 February (2019 Scheme) · 100 marks · 180 min

Question

Draw the structure of HIV and label. Add a note on its transmission (2.5+1.5)

Q104 marksShort Answers

Answer

Structure to draw and label: a spherical enveloped virion (~100–120 nm) — outer lipid envelope studded with gp120 (CD4 attachment) and gp41 (membrane fusion) glycoproteins; matrix protein (p17) beneath the envelope; conical capsid (p24 core) enclosing two copies of single-stranded RNA genome along with reverse transcriptase, integrase, and protease enzymes.

Transmission

  • Sexual contact — the predominant route
  • Blood and blood products — transfusion, needle-sharing among injecting drug users
  • Vertical transmission — in utero, intrapartum, and via breastfeeding
  • Occupational needle-stick exposure
  1. 1General Properties of Viruses and Virus Host Interaction

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