Revise MBBS

Paper I — 2025 March (Supplementary (SAY)) (2019 Scheme) — Qxiv

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Paper I
2025 March (Supplementary (SAY)) (2019 Scheme) · 100 marks · 180 min

Question

Patient: Mrs. Rose, a 68-year-old woman, Chief Complaint: Gradual loss of vision in both eyes, particularly in the peripheral vision. Medical History: Hypertension, Type 2 Diabetes, and Hyperlipidaemia. No known drug allergies. Family History: Her father had glaucoma. Presenting Symptoms: Mrs. Rose reports difficulty seeing objects in her peripheral vision for the past 6 months. She has had a gradual decrease in her night vision as well. Ophthalmologic Exam: Intraocular pressure (IOP): 28 mmHg in both eyes Visual field: Decreased peripheral vision, with a loss in the superior field. Optic disc: Cupping noted in both eyes. Diagnosis: Open-angle glaucoma.

The drug that should be used cautiously in Mrs. Rose, who has a history of bronchial asthma

  • a) Latanoprost
  • b) Brimonidine
  • c) Timolol
  • d) Acetazolamide
Qxiv1 marksMCQs (Case)

Answer

Correct answer: c) Timolol

Timolol is a non-selective beta-blocker; even as a topical eye-drop, systemic absorption is sufficient to precipitate bronchospasm in patients with bronchial asthma via beta-2 receptor blockade, so it must be used cautiously (or avoided) in this patient. Latanoprost, brimonidine, and acetazolamide do not carry this specific respiratory risk.

  1. 1Cholinergic System

Other Years Asked

  1. 1(2024 March (Supplementary) (2019 Scheme)Short Essay · 8 marks
  2. 2(2023 July (Supplementary) (2019 Scheme)Short Essay · 8 marks
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  4. 4Enumerate the topical group of agents used in the treatment of open angle glaucoma. Give examples and explain the mechanism of action of each group of drugs. (2+2+2)2019 February (2010 Scheme)Essay · 6 marks
  5. 5Read the clinical problem and answer the following questions:2017 August (Supplementary) (2010 Scheme)Essay · 6 marks
  6. 6min. He gives history of spraying a strong insecticide in his agricultural field. (2023 March (Supplementary) (2010 Scheme)Essay · 6 marks
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  9. 9Classify atropine substitutes, explain their uses and adverse effects (3+2+1)2022 May (Supplementary) (2010 Scheme)Essay · 6 marks
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  12. 12Therapeutic uses and adverse effects of Neostigmine2022 February (2019 Scheme)Short Answer · 4 marks
  13. 13Pharmacotherapy of Organophosphorous poisoning2022 July (Supplementary) (2019 Scheme)Short Answer · 4 marks
  14. 14Pharmacological basis for the use of Timolol in glaucoma.2024 June (Supplementary) (2019 Scheme)Short Answer · 4 marks
  15. 15Pharmacological management of Myasthenia gravis.2022 July (Supplementary) (2019 Scheme)Short Answer · 4 marks
  16. 16Treatment of organophosphorus poisoning2013 September (Supplementary) (2010 Scheme)Short Note · 3 marks
  17. 17Drug treatment of anti cholinesterase poisoning2013 April (2010 Scheme)Short Note · 3 marks
  18. 18Neostigmine2021 December (Supplementary) (2010 Scheme)Short Note · 3 marks
  19. 19Treatment of organophosphorous poisoning2014 September (Supplementary) (2010 Scheme)Short Note · 3 marks
  20. 20Atropine2015 February (2010 Scheme)Short Note · 3 marks
  21. 21Therapeutic uses and adverse effects of atropine.2016 October (Supplementary) (2010 Scheme)Short Note · 3 marks
  22. 22Neostigmine.2017 August (Supplementary) (2010 Scheme)Short Note · 3 marks
  23. 23Edrophonium2018 February (2010 Scheme)Short Note · 3 marks
  24. 24Pralidoxime in organophosphate compound poisoning2021 December (Supplementary) (2010 Scheme)Short Answer · 1 mark
  25. 25Toxicities of atropine include the following: 1. Bradycardia 2. Dry mouth 3. Miosis 4. Psychotic behavior2024 December (Supplementary) (2019 Scheme)MCQ · 1 mark
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  27. 27Explain briefly why physostigmine is preferred over neostigmine for the treatment of glaucoma.2015 February (2010 Scheme)Short Answer · 1 mark
  28. 28Anti- muscarinic drugs2017 August (Supplementary) (2010 Scheme)Short Answer · 1 mark
  29. 29Drugs used in myasthenia gravis.2016 October (Supplementary) (2010 Scheme)Short Answer · 1 mark
  30. 30Assertion (A): Pralidoxime is most specific drug for organophosphate poisoning. Reason (R): Organophosphates block AChE enzyme2025 March (Supplementary (SAY)) (2019 Scheme)MCQ (A/R) · 1 mark
  31. 31Management of organophosphorus poisoning.2016 February (2010 Scheme)Short Answer · 1 mark
  32. 32Trihexyphenidyl in the treatment of Drug induced parkinsonism2024 August (Supplementary) (2010 Scheme)Short Answer · 1 mark
  33. 33Explain the rationale for the use of oximes in organophosphorus poisoning.2017 August (Supplementary) (2010 Scheme)Short Answer · 1 mark
  34. 34Rationale for use of pilocarpine in glaucoma2018 July (Supplementary) (2010 Scheme)Short Answer · 1 mark
  35. 35Two uses and two adverse effects of atropine2014 March (2010 Scheme)Short Answer · 1 mark
  36. 36Rationale for use of physostigmine in atropine poisoning2015 September (Supplementary) (2010 Scheme)Short Answer · 1 mark
  37. 37Rationale for the use of glycopyrrolate in pre-anesthetic medication.2016 October (Supplementary) (2010 Scheme)Short Answer · 1 mark
  38. 38Cholinesterase reactivators2015 September (Supplementary) (2010 Scheme)Short Answer · 1 mark
  39. 39Atropine as antisecretory agent2019 February (2010 Scheme)Short Answer · 1 mark
  40. 40The preferred first-line pharmacologic treatment for open-angle glaucoma is:2025 March (Supplementary (SAY)) (2019 Scheme)MCQ (Case) · 1 mark
  41. 41Used in treatment of acute congestive glaucoma2018 February (2010 Scheme)Short Answer · 1 mark
  42. 42Why is benzhexol used in the treatment of drug induced Parkinsonism.2018 February (2010 Scheme)Short Answer · 1 mark
  43. 43Drugs used in Myasthenia gravis2013 April (2010 Scheme)Short Answer · 1 mark
  44. 44Trihexyphenidyl in drug induced extrapyramidal syndrome2021 May (Supplementary) (2010 Scheme)Short Answer · 1 mark
  45. 45The Vasicoselective anticholinergic used in urinary frequency, urgency, and dysuria is2025 March (Supplementary (SAY)) (2019 Scheme)MCQ · 1 mark
  46. 46Bronchodilators (of two different groups)2013 September (Supplementary) (2010 Scheme)Short Answer · 1 mark
  47. 47Vesico-selective anticholinergics2020 February (Supplementary) (2010 Scheme)Short Answer · 0.3 marks
  48. 48Levodopa in Drug induced parkinsonism. Name the following (Two examples for each): (5x1=5)2025 March (Supplementary) (2010 Scheme)Short Answer · 0.3 marks
  49. 49 Ketoconazole in fungal meningitis Name the following (Two examples for each) (5x1=5)2019 July (Supplementary) (2010 Scheme)Short Answer · 0.3 marks
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  51. 51 Neostigmine in glaucoma management Name the following (Two examples for each): (5x1=5)2020 February (Supplementary) (2010 Scheme)Short Answer · 0.3 marks
  52. 52Anticholinesterases2024 August (Supplementary) (2010 Scheme)Short Answer · 0.3 marks
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  57. 57Pyridostigmine for the diagnosis of Myasthenia gravis.2022 February (2019 Scheme)Short Answer · 0.2 marks
  58. 58Drugs used to treat Organophosphorus poisoning2022 February (2019 Scheme)Short Answer · 0.2 marks
  59. 59Vasicoselective anticholinergics.2023 January (Supplementary) (2019 Scheme)Short Answer · 0.2 marks
  60. 60Benzhexol in chlorpromazine induced Parkinsonism Name the following (Two examples for each): (8x1=8)2023 January (Supplementary) (2019 Scheme)Short Answer · 0.2 marks

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