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Paper I — 2018 July (Supplementary) (2010 Scheme) — Q9

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Paper I
2018 July (Supplementary) (2010 Scheme) · 40 marks · 120 min

Question

Rationale for use of pilocarpine in glaucoma

Q91 marksShort Answers

Answer

Pilocarpine is a direct-acting muscarinic agonist. Topically applied, it stimulates M3 receptors in the ciliary muscle and iris sphincter, causing contraction of the ciliary muscle (which pulls open the trabecular meshwork, increasing aqueous humour outflow) and miosis (which pulls the iris away from the angle in angle-closure glaucoma, relieving obstruction to aqueous outflow). Both effects reduce intraocular pressure, making it useful in both open-angle and acute angle-closure glaucoma (the latter as an emergency adjunct).

  1. 1Cholinergic System

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  1. 1(2024 March (Supplementary) (2019 Scheme)Short Essay · 8 marks
  2. 2(2023 July (Supplementary) (2019 Scheme)Short Essay · 8 marks
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  14. 14Pharmacological basis for the use of Timolol in glaucoma.2024 June (Supplementary) (2019 Scheme)Short Answer · 4 marks
  15. 15Pharmacological management of Myasthenia gravis.2022 July (Supplementary) (2019 Scheme)Short Answer · 4 marks
  16. 16Treatment of organophosphorus poisoning2013 September (Supplementary) (2010 Scheme)Short Note · 3 marks
  17. 17Drug treatment of anti cholinesterase poisoning2013 April (2010 Scheme)Short Note · 3 marks
  18. 18Neostigmine2021 December (Supplementary) (2010 Scheme)Short Note · 3 marks
  19. 19Treatment of organophosphorous poisoning2014 September (Supplementary) (2010 Scheme)Short Note · 3 marks
  20. 20Atropine2015 February (2010 Scheme)Short Note · 3 marks
  21. 21Therapeutic uses and adverse effects of atropine.2016 October (Supplementary) (2010 Scheme)Short Note · 3 marks
  22. 22Neostigmine.2017 August (Supplementary) (2010 Scheme)Short Note · 3 marks
  23. 23Edrophonium2018 February (2010 Scheme)Short Note · 3 marks
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  29. 29Anti- muscarinic drugs2017 August (Supplementary) (2010 Scheme)Short Answer · 1 mark
  30. 30Drugs used in myasthenia gravis.2016 October (Supplementary) (2010 Scheme)Short Answer · 1 mark
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  34. 34Explain the rationale for the use of oximes in organophosphorus poisoning.2017 August (Supplementary) (2010 Scheme)Short Answer · 1 mark
  35. 35Two uses and two adverse effects of atropine2014 March (2010 Scheme)Short Answer · 1 mark
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  37. 37Rationale for the use of glycopyrrolate in pre-anesthetic medication.2016 October (Supplementary) (2010 Scheme)Short Answer · 1 mark
  38. 38Cholinesterase reactivators2015 September (Supplementary) (2010 Scheme)Short Answer · 1 mark
  39. 39Atropine as antisecretory agent2019 February (2010 Scheme)Short Answer · 1 mark
  40. 40The preferred first-line pharmacologic treatment for open-angle glaucoma is:2025 March (Supplementary (SAY)) (2019 Scheme)MCQ (Case) · 1 mark
  41. 41Used in treatment of acute congestive glaucoma2018 February (2010 Scheme)Short Answer · 1 mark
  42. 42Why is benzhexol used in the treatment of drug induced Parkinsonism.2018 February (2010 Scheme)Short Answer · 1 mark
  43. 43Drugs used in Myasthenia gravis2013 April (2010 Scheme)Short Answer · 1 mark
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