Revise MBBS

Paper I — 2025 March (Supplementary (SAY)) (2019 Scheme) — Qxi

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Paper I
2025 March (Supplementary (SAY)) (2019 Scheme) · 100 marks · 180 min

Question

Patient: Mrs. Rose, a 68-year-old woman, Chief Complaint: Gradual loss of vision in both eyes, particularly in the peripheral vision. Medical History: Hypertension, Type 2 Diabetes, and Hyperlipidaemia. No known drug allergies. Family History: Her father had glaucoma. Presenting Symptoms: Mrs. Rose reports difficulty seeing objects in her peripheral vision for the past 6 months. She has had a gradual decrease in her night vision as well. Ophthalmologic Exam: Intraocular pressure (IOP): 28 mmHg in both eyes Visual field: Decreased peripheral vision, with a loss in the superior field. Optic disc: Cupping noted in both eyes. Diagnosis: Open-angle glaucoma.

The preferred first-line pharmacologic treatment for open-angle glaucoma is:

  • a) Pilocarpine
  • b) Latanoprost
  • c) Brimonidine
  • d) Acetazolamide
Qxi1 marksMCQs (Case)

Answer

Correct answer: b) Latanoprost

Prostaglandin analogues (e.g. Latanoprost) are the preferred first-line agents for open-angle glaucoma — once-daily dosing, strong IOP-lowering effect via increased uveoscleral outflow, and a favourable systemic safety profile.

  1. 1Cholinergic System

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  36. 36Two uses and two adverse effects of atropine2014 March (2010 Scheme)Short Answer · 1 mark
  37. 37Rationale for use of physostigmine in atropine poisoning2015 September (Supplementary) (2010 Scheme)Short Answer · 1 mark
  38. 38Rationale for the use of glycopyrrolate in pre-anesthetic medication.2016 October (Supplementary) (2010 Scheme)Short Answer · 1 mark
  39. 39Cholinesterase reactivators2015 September (Supplementary) (2010 Scheme)Short Answer · 1 mark
  40. 40Atropine as antisecretory agent2019 February (2010 Scheme)Short Answer · 1 mark
  41. 41Used in treatment of acute congestive glaucoma2018 February (2010 Scheme)Short Answer · 1 mark
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