Paper I
2022 July (Supplementary) (2019 Scheme) · 100 marks · 180 min

Question

Loratadine/Chlorpheniramine maleate for Acute Rhinitis in a driver

Q130.2 marksShort Answers

Answer

Loratadine is the appropriate choice — a second-generation antihistamine with poor blood-brain-barrier penetration, giving minimal sedation, safe for a patient who needs to drive. Chlorpheniramine maleate, a first-generation antihistamine, crosses the blood-brain barrier and causes significant sedation and impaired psychomotor performance, making it unsafe for a driver despite being equally effective against the allergic rhinitis itself.

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