Paper I
2022 May (Supplementary) (2010 Scheme) · 40 marks · 120 min

Question

Dextran

Q131 marksShort Answers

Answer

Uses: Plasma volume expansion in hypovolemic shock (colloid, high oncotic effect); Prophylaxis of postoperative venous thromboembolism (reduces blood viscosity and platelet adhesiveness)

Adverse effects: Anaphylactoid hypersensitivity reactions; Interference with blood group cross-matching (coats red cells) and bleeding tendency at high doses

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