Question
Aprepitant
Q11 1 marks Short Answers ★ ✓
Answer
Aprepitant is a neurokinin-1 (NK1) receptor antagonist. It blocks the binding of substance P to NK1 receptors in the central nervous system (area postrema/chemoreceptor trigger zone), making it effective in preventing both the acute and, particularly, the delayed phase of chemotherapy-induced nausea and vomiting (especially with highly emetogenic chemotherapy like cisplatin), typically used in combination with a 5-HT3 antagonist and dexamethasone.
1 Antiemetics
Other Years Asked
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any one group.
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Name the following (Two examples for each): (8x1=8) 2022 February (2019 Scheme) Short Answer · 0.2 marks 23 Prokinetic agents. 2023 July (Supplementary) (2019 Scheme) Short Answer · 0.2 marks 
