Paper II
2025 March (Supplementary (SAY)) (2019 Scheme) · 100 marks · 180 min

Question

The potent inhibitor of bacterial cell wall synthesis used for Neisseria gonorrhoeae infections is:

  • a) Ceftriaxone
  • c) Erythromycin
  • b) Clindamycin
  • d) Trimethoprim-sulfamethoxazole
Qiii1 marksMCQs

Answer

Correct answer: a) Ceftriaxone

Ceftriaxone, a third-generation cephalosporin, inhibits bacterial cell wall (peptidoglycan) synthesis via penicillin-binding protein binding, and is the current recommended single-dose treatment for gonorrhoea, given reliable efficacy and the widespread resistance Neisseria gonorrhoeae has developed to older agents.

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