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Paper II — 2022 February (2019 Scheme) — Q16

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Paper II
2022 February (2019 Scheme) · 100 marks · 180 min

Question

Drugs for herpes simplex

Q160.2 marksShort Answers

Answer

Acyclovir, Valacyclovir — guanosine analogues, selectively phosphorylated by HSV-encoded thymidine kinase and incorporated into viral DNA as chain terminators; valacyclovir is a prodrug of acyclovir with improved oral bioavailability.

  1. 1Antiviral Drugs

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  1. 1A Resident surgeon consults a physician with the following problem: During a surgical procedure he got exposed to a 26-year-old female patient’s blood and saliva through a piercing injury on the finger. A needle had penetrated across his gloves and skin to a depth of 2–3 mm, but was withdrawn immediately and the area washed under running water. On enquiry, the patient revealed that one year back she had tested HIV (Human Immunodeficiency Viru2024 June (Supplementary) (2019 Scheme)Essay · 15 marks
  2. 2(2022 July (Supplementary) (2019 Scheme)Essay · 8 marks
  3. 3Pharmacological basis for the use of Zidovudine in HIV.2023 July (Supplementary) (2019 Scheme)Short Answer · 4 marks
  4. 4Write briefly on post-exposure prophylaxis of HIV infection after a needlestick injury.2024 December (Supplementary) (2019 Scheme)Short Answer · 4 marks
  5. 5Acyclovir2023 January (Supplementary) (2019 Scheme)Short Answer · 4 marks
  6. 6Protease inhibitors2019 February (2010 Scheme)Short Note · 3 marks
  7. 7Protease inhibitors in HIV infection.2017 February (2010 Scheme)Short Note · 3 marks
  8. 8Acyclovir2024 March (Supplementary) (2010 Scheme)Short Note · 3 marks
  9. 9Oseltamivir2019 July (Supplementary) (2010 Scheme)Short Note · 3 marks
  10. 10For herpes virus infection2018 July (Supplementary) (2010 Scheme)Short Answer · 1 mark
  11. 11Antiretroviral drugs2016 October (Supplementary) (2010 Scheme)Short Answer · 1 mark
  12. 12Mechanism of action of oseltamivir.2013 September (Supplementary) (2010 Scheme)Short Answer · 1 mark
  13. 13Non nucleoside reverse transcriptase inhibitors2016 February (2010 Scheme)Short Answer · 1 mark
  14. 14H1N1 viral infection.2015 September (Supplementary) (2010 Scheme)Short Answer · 1 mark
  15. 15Mechanism of action of acyclovir2013 April (2010 Scheme)Short Answer · 1 mark
  16. 16Retro viral infections2014 September (Supplementary) (2010 Scheme)Short Answer · 1 mark
  17. 17Post exposure prophylaxis of HIV (acquired immunodeficiency syndrome)2017 August (Supplementary) (2010 Scheme)Short Answer · 1 mark
  18. 18Herpes zoster infection.2017 February (2010 Scheme)Short Answer · 1 mark
  19. 19Protease inhibitors2018 February (2010 Scheme)Short Answer · 1 mark
  20. 20HIV infection..2013 September (Supplementary) (2010 Scheme)Short Answer · 1 mark
  21. 21Non-nucleoside Reverse Transcriptase Inhibitors (nNRTIs)2020 February (Supplementary) (2010 Scheme)Short Answer · 0.3 marks
  22. 22Antiretroviral drugs2023 July (Supplementary) (2010 Scheme)Short Answer · 0.3 marks
  23. 23Protease inhibitors2025 March (Supplementary) (2010 Scheme)Short Answer · 0.3 marks
  24. 24Neuraminidase inhibitors2022 May (Supplementary) (2010 Scheme)Short Answer · 0.3 marks
  25. 25Anti-herpes virus drugs2021 December (Supplementary) (2010 Scheme)Short Answer · 0.3 marks
  26. 26Anti Hepatitis B viral drugs2021 May (Supplementary) (2010 Scheme)Short Answer · 0.3 marks
  27. 27Post-exposure prophylaxis in HIV infection2022 October (Supplementary) (2010 Scheme)Short Answer · 0.3 marks
  28. 28Anti-influenza virus drugs2025 August (Supplementary) (2010 Scheme)Short Answer · 0.3 marks
  29. 29Antiretroviral drugs.2023 January (Supplementary) (2019 Scheme)Short Answer · 0.2 marks
  30. 30Drugs to treat Influenza.2023 July (Supplementary) (2019 Scheme)Short Answer · 0.2 marks
  31. 31Neuraminidase inhibitors2024 March (Supplementary) (2019 Scheme)Short Answer · 0.2 marks

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