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Paper II — 2021 February (Supplementary) (2010 Scheme) — Q14

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Paper II
2021 February (Supplementary) (2010 Scheme)

Question

Ciprofloxacin/Norfloxacin in urinary tract infection

Q140.3 marksShort Answers

Answer

Chosen drug: Ciprofloxacin

Justification: Ciprofloxacin has broader systemic bioavailability, better tissue penetration, and a more established role for both uncomplicated and complicated urinary tract infections (including upper tract/pyelonephritis), whereas norfloxacin has lower systemic bioavailability and is generally reserved for uncomplicated lower UTIs (cystitis) only, since its lower plasma concentrations make it less reliable for infections beyond the bladder — making ciprofloxacin the more broadly appropriate choice.

  1. 1Antimicrobials General Considerations

Other Years Asked

  1. 1(2023 July (Supplementary) (2019 Scheme)Short Essay · 8 marks
  2. 2Read the clinical problem and answer the following questions: 40 years old man who was on metronidazole for amoebic dysentery went to a cocktail party where he consumed alcohol. After some time, he started developing symptoms like flushing, burning sensation, throbbing headache, dizziness, tightness in chest, vomiting.2014 March (2010 Scheme)Essay · 6 marks
  3. 3Explain prophylactic use of antimicrobials giving suitable examples.2024 December (Supplementary) (2019 Scheme)Short Essay · 6 marks
  4. 4Pharmacological basis for the use of Benzathine Penicillin in Rheumatic fever prophylaxis.2023 July (Supplementary) (2019 Scheme)Short Answer · 4 marks
  5. 5Management of Hospital Acquired Infections.2023 July (Supplementary) (2019 Scheme)Short Answer · 4 marks
  6. 6Metronidazole.2013 September (Supplementary) (2010 Scheme)Short Note · 3 marks
  7. 7Superinfection2021 December (Supplementary) (2010 Scheme)Short Note · 3 marks
  8. 8Antibiotic resistance2019 July (Supplementary) (2010 Scheme)Short Note · 3 marks
  9. 9Metronidazole2013 April (2010 Scheme)Short Note · 3 marks
  10. 10Metronidazole2017 August (Supplementary) (2010 Scheme)Short Note · 3 marks
  11. 11Burns infected with pseudomonas aeruginosa2015 September (Supplementary) (2010 Scheme)Short Answer · 1 mark
  12. 12Chemoprophylaxis of surgical site infection2013 April (2010 Scheme)Short Answer · 1 mark
  13. 13Vancomycin2021 May (Supplementary) (2010 Scheme)Short Answer · 1 mark
  14. 14Specify the important spectrum of vancomycin2014 September (Supplementary) (2010 Scheme)Short Answer · 1 mark
  15. 15Prophylaxis of rheumatic fever2017 August (Supplementary) (2010 Scheme)Short Answer · 1 mark
  16. 16Mention four uses of metronidazole2016 October (Supplementary) (2010 Scheme)Short Answer · 1 mark
  17. 17Rationale of combining trimethoprim with sulfamethoxazole2018 February (2010 Scheme)Short Answer · 1 mark
  18. 18Urinary tract infections2014 September (Supplementary) (2010 Scheme)Short Answer · 1 mark
  19. 19What is post antibiotic effect and mention one example2016 October (Supplementary) (2010 Scheme)Short Answer · 1 mark
  20. 20Assertion (A): Ticarcillin is combined with Gentamicin for Pseudomonas infection, especially in neutropenic patients. Reason (R): Ticarcillin inhibits cell wall synthesis and Gentamicin inhibits protein synthesis and both of them are bactericidal.2024 December (Supplementary) (2019 Scheme)MCQ · 1 mark
  21. 21Prevention of AIDS in the new born2013 April (2010 Scheme)Short Answer · 1 mark
  22. 22Pseudomembranous colitis.2013 September (Supplementary) (2010 Scheme)Short Answer · 1 mark
  23. 23Drugs for urinary tract infection2022 October (Supplementary) (2010 Scheme)Short Answer · 0.3 marks

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