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Paper II — 2016 October (Supplementary) (2010 Scheme) — Q11

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Paper II
2016 October (Supplementary) (2010 Scheme) · 40 marks · 120 min

Question

What is post antibiotic effect and mention one example

Q111 marksShort Answers

Answer

Post-antibiotic effect (PAE) is the persistent suppression of bacterial growth that continues even after the plasma concentration of the antibiotic has fallen below the minimum inhibitory concentration (MIC). It allows for extended dosing intervals for antibiotics that exhibit a significant PAE. Example: Aminoglycosides (e.g., Gentamicin) show a pronounced PAE against Gram-negative bacteria, which is part of the rationale for their once-daily dosing.

  1. 1Antimicrobials General Considerations

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  14. 14Specify the important spectrum of vancomycin2014 September (Supplementary) (2010 Scheme)Short Answer · 1 mark
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  16. 16Mention four uses of metronidazole2016 October (Supplementary) (2010 Scheme)Short Answer · 1 mark
  17. 17Rationale of combining trimethoprim with sulfamethoxazole2018 February (2010 Scheme)Short Answer · 1 mark
  18. 18Urinary tract infections2014 September (Supplementary) (2010 Scheme)Short Answer · 1 mark
  19. 19Assertion (A): Ticarcillin is combined with Gentamicin for Pseudomonas infection, especially in neutropenic patients. Reason (R): Ticarcillin inhibits cell wall synthesis and Gentamicin inhibits protein synthesis and both of them are bactericidal.2024 December (Supplementary) (2019 Scheme)MCQ · 1 mark
  20. 20Prevention of AIDS in the new born2013 April (2010 Scheme)Short Answer · 1 mark
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  23. 23Norfloxacin in urinary tract infection2021 February (Supplementary) (2010 Scheme)Short Answer · 0.3 marks

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