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Paper II — 2018 February (2010 Scheme) — Q6

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Paper II
2018 February (2010 Scheme) · 40 marks · 120 min

Question

Albendazole

Q63 marksShort Notes

Answer

Albendazole is a broad-spectrum benzimidazole anthelmintic.

Mechanism of action

  • Binds to helminth β-tubulin, inhibiting microtubule polymerization
  • Impairs glucose uptake and cellular processes in the parasite, leading to depletion of glycogen stores, decreased ATP production, and parasite death

Uses

  • Roundworm (Ascariasis), Hookworm, Whipworm, Pinworm infestations
  • Strongyloidiasis
  • Hydatid disease (Echinococcosis)
  • Neurocysticercosis
  • Filariasis (as part of mass drug administration)

Adverse effects

  • GI upset
  • Headache
  • Hepatotoxicity with prolonged use
  • Teratogenic — avoided in pregnancy
  1. 1Anthelmintic Drugs

Other Years Asked

  1. 1Albendazole2024 June (Supplementary) (2019 Scheme)Short Answer · 4 marks
  2. 2Albendazole.2023 January (Supplementary) (2019 Scheme)Short Answer · 4 marks
  3. 3Ivermectin2022 February (2019 Scheme)Short Answer · 4 marks
  4. 4Albendazole2023 March (Supplementary) (2010 Scheme)Short Note · 3 marks
  5. 5Ivermectin.2013 September (Supplementary) (2010 Scheme)Short Note · 3 marks
  6. 6Ivermectin2021 February (Supplementary) (2010 Scheme)Short Note · 3 marks
  7. 7Albendazole2024 March (Supplementary) (2010 Scheme)Short Note · 3 marks
  8. 8Filariasis.2013 September (Supplementary) (2010 Scheme)Short Answer · 1 mark
  9. 9Diethylcarbamazine citrate (DEC)2023 July (Supplementary) (2010 Scheme)Short Answer · 1 mark
  10. 10Treatment of ascariasis2015 February (2010 Scheme)Short Answer · 1 mark
  11. 11Round worm infestation2016 October (Supplementary) (2010 Scheme)Short Answer · 1 mark
  12. 12Treatment of onchocercosis2016 February (2010 Scheme)Short Answer · 1 mark
  13. 13Hookworm infestation2015 September (Supplementary) (2010 Scheme)Short Answer · 1 mark
  14. 14In treatment of filariasis2018 July (Supplementary) (2010 Scheme)Short Answer · 1 mark
  15. 15Mebendazole2020 February (Supplementary) (2010 Scheme)Short Answer · 1 mark
  16. 16Treatment of hook worm infestation2018 February (2010 Scheme)Short Answer · 1 mark
  17. 17Albendazole2022 May (Supplementary) (2010 Scheme)Short Answer · 1 mark
  18. 18Ivermectin2022 October (Supplementary) (2010 Scheme)Short Answer · 1 mark
  19. 19Diethylcarbamazine citrate2021 May (Supplementary) (2010 Scheme)Short Answer · 1 mark
  20. 20Ivermectin2023 March (Supplementary) (2010 Scheme)Short Answer · 1 mark
  21. 21Drugs effective in Round worm infestations.2019 July (Supplementary) (2010 Scheme)Short Answer · 0.3 marks
  22. 22Drugs used for treatment of Filariasis2024 March (Supplementary) (2019 Scheme)Short Answer · 0.2 marks
  23. 23Drugs to treat Filariasis.2023 July (Supplementary) (2019 Scheme)Short Answer · 0.2 marks
  24. 24Drugs for treating Filariasis.2023 January (Supplementary) (2019 Scheme)Short Answer · 0.2 marks

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