Paper I — 2021 February (Supplementary) (2010 Scheme) — Q15

Paper I

2021 February (Supplementary) (2010 Scheme) · 40 marks · 120 min

Question

Frusemide/Hydrochlorothiazide as antihypertensive Name the following (Two examples for each): (5x1=5)

Q150.3 marksShort Answers★✓

Answer

Chosen drug: Hydrochlorothiazide

Justification: Hydrochlorothiazide (a thiazide diuretic) is preferred as an antihypertensive because it has a moderate, sustained natriuretic effect suitable for chronic once-daily oral therapy with a well-established mortality benefit in hypertension trials. Furosemide (a loop diuretic) has a more potent but shorter-duration diuretic effect, better suited to oedematous states (heart failure, renal impairment) than as a routine first-line antihypertensive, and is generally reserved for hypertension with significant renal impairment or volume overload.

Related Concepts

1. 1Drugs for Heart Failure

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