Paper I — 2025 March (Supplementary) (2010 Scheme) — Q9

Paper I

2025 March (Supplementary) (2010 Scheme) · 40 marks · 120 min

Question

Dopamine in Cardiogenic shock.

Q91 marksShort Answers★✓

Answer

Dopamine is used in cardiogenic shock because its dose-dependent receptor actions provide inotropic and vasopressor support while preserving perfusion to vital organs: at low doses, D1-receptor-mediated renal/splanchnic vasodilation maintains organ perfusion; at moderate doses, beta-1-mediated positive inotropy increases cardiac output; at high doses, alpha-1-mediated vasoconstriction raises blood pressure. This dose-titratable, multi-receptor profile makes it useful for supporting a failing circulation while cardiac contractility and blood pressure are both compromised.

Related Concepts

1. 1Drugs for Heart Failure

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