Paper I
2025 March (Supplementary (SAY)) (2019 Scheme) · 100 marks · 180 min

Question

Which of the following drugs can cause QT prolongation

  1. Amiodarone
  2. Doxorubicin
  3. Ibuprofen
  4. Erythromycin a) 1 & 4 are correct b) 3 & 4 are correct c) 1 & 3 are correct d) 2 & 4 are correct
  • a) 1 & 4 are correct
  • b) 3 & 4 are correct
  • c) 1 & 3 are correct
  • d) 2 & 4 are correct
Qvi1 marksMCQs (Multi)

Answer

Correct answer: a) 1 & 4 are correct

Amiodarone (Class III, K⁺ channel blockade) and Erythromycin (macrolide, hERG channel blockade) are both well-established causes of QT prolongation. Doxorubicin’s cardiotoxicity is via cardiomyopathy, not QT prolongation, and ibuprofen does not typically prolong the QT interval.

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