Paper I
2013 April (2010 Scheme) · 40 marks · 180 min

Question

Clinical uses of prostaglandins

Q91 marksShort Answers

Answer

  • Obstetric: Induction of labour (Oxytocin, Dinoprostone), termination of pregnancy/abortion (Misoprostol, Dinoprostone), cervical ripening, postpartum haemorrhage (Carboprost)
  • GI: Misoprostol — prevention of NSAID-induced peptic ulcers, treatment of peptic ulcer
  • Cardiovascular: Alprostadil (PGE1) — to maintain patency of ductus arteriosus in congenital heart disease (before surgery); erectile dysfunction
  • Ophthalmic: Latanoprost — glaucoma (reduces intraocular pressure)
  • Pulmonary: Epoprostanol — pulmonary arterial hypertension

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