Paper I
2018 July (Supplementary) (2010 Scheme) · 40 marks · 120 min

Question

Uses of prostaglandins

Q73 marksShort Notes

Answer

  • Obstetric: Induction of labour (Oxytocin, Dinoprostone), termination of pregnancy (Misoprostol, Dinoprostone), postpartum haemorrhage (Carboprost)
  • GI: Misoprostol — prevention/treatment of NSAID-induced peptic ulcers
  • Cardiovascular: Alprostadil (PGE1) — maintains patency of ductus arteriosus in congenital heart disease before surgery; erectile dysfunction
  • Ophthalmic: Latanoprost — glaucoma (reduces intraocular pressure)
  • Pulmonary: Epoprostenol — pulmonary arterial hypertension

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