Paper I
2020 February (Supplementary) (2010 Scheme) · 40 marks · 120 min

Question

A middle aged man posted for Appendisectomy was given an injection by the ward nurse before being shifted to the operation theatre. Patient developed dryness of mouth, difficulty in swallowing and severe thirst.  What is the drug that was injected  Why the drug was given pre-operatively  What are the other drugs which are given pre-operatively (1+2+3)

Q26 marksEssays

Answer

(a) Drug injected

  • Atropine (or Glycopyrrolate) — an anticholinergic, given as preanaesthetic medication; the symptoms described (dry mouth, difficulty swallowing, thirst) are classic peripheral antimuscarinic effects

(b) Why given pre-operatively

  • To reduce salivary and bronchial secretions (preventing aspiration and easing intubation)
  • To prevent vagally-mediated reflex bradycardia during airway manipulation/anaesthetic induction

(c) Other drugs given pre-operatively

  • Benzodiazepines (e.g., Midazolam) — for anxiolysis/sedation
  • Opioids (e.g., Fentanyl, Morphine) — for analgesia and to reduce anaesthetic requirement
  • Antiemetics (e.g., Ondansetron) — to prevent postoperative nausea/vomiting
  • H2 blockers/PPIs (e.g., Ranitidine) — to reduce gastric acidity and aspiration risk

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