Paper I
2022 October (Supplementary) (2010 Scheme) · 40 marks · 120 min

Question

Pre-anaesthetic medication

Q73 marksShort Notes

Answer

Pre-anesthetic medication (premedication) is given before general anesthesia to make induction smoother and safer.

Objectives and drug groups used:

  • Anxiolysis — Benzodiazepines (Diazepam, Midazolam)
  • Reduce secretions and vagal reflexes — Anticholinergics (Glycopyrrolate, Atropine)
  • Analgesia — Opioids (Morphine, Fentanyl)
  • Antiemetic prophylaxis — Ondansetron, Metoclopramide
  • Reduce anesthetic requirement — sedatives/opioids allow a lower dose of the general anesthetic itself

Overall benefits: reduced anxiety, decreased anesthetic dose requirement, smoother induction/emergence, reduced secretions and vagally-mediated bradycardia, and antiemetic/analgesic cover extending into the immediate post-operative period.

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