Question
Sevoflurane
Q4 3 marks Short Notes ★ ✓
Answer
Sevoflurane is a halogenated inhalational general anaesthetic.
Properties
Low blood-gas solubility → rapid, smooth induction and recovery
Pleasant, non-pungent odour — well suited for inhalational induction, especially in children
Moderate potency
Effects
Mild myocardial depression, less arrhythmogenic than halothane (does not sensitize the heart to catecholamines to the same degree)
Bronchodilator
Minimal airway irritation
Adverse effects
Can be degraded by soda lime to Compound A (nephrotoxic in animal studies; clinical significance in humans debated) — avoided with low fresh gas flows for prolonged periods
Postoperative shivering, nausea/vomiting
Malignant hyperthermia (rare, as with other halogenated agents)
Widely used for both induction (especially paediatric) and maintenance of anaesthesia due to its favourable safety and recovery profile.
1 General Anaesthetics
Other Years Asked
1 Classify general anaesthetics. Write the mechanism of action, uses and adverse effects
of Halothane. Enumerate four drugs used as pre-anaesthetic medication with its
rationale for use. Discuss the management of Morphine poisoning. (4+3+6+2) 2024 June (Supplementary) (2019 Scheme) Essay · 15 marks 2 Compare Inhalational and intravenous general anesthetics (4+4) 2024 March (Supplementary) (2019 Scheme) Short Essay · 8 marks 3 A middle aged man posted for Appendisectomy was given an injection by the ward
nurse before being shifted to the operation theatre. Patient developed dryness of
mouth, difficulty in swallowing and severe thirst.
What is the drug that was injected
Why the drug was given pre-operatively
What are the other drugs which are given pre-operatively (1+2+3) 2020 February (Supplementary) (2010 Scheme) Essay · 6 marks 4 Classify general anaesthetics - four groups with two examples. Add a brief note on pre anaesthetic
medication (4+2) 2025 March (Supplementary (SAY)) (2019 Scheme) Short Essay · 6 marks 5 Propofol. 2023 January (Supplementary) (2019 Scheme) Short Answer · 4 marks 6 Enumerate four objectives of preanesthetic medications along with the drugs used for
achieving the same. 2024 December (Supplementary) (2019 Scheme) Short Answer · 4 marks 7 Halothane 2022 May (Supplementary) (2010 Scheme) Short Note · 3 marks 8 Pre-anaesthetic medication 2022 October (Supplementary) (2010 Scheme) Short Note · 3 marks 9 Propofol 2018 February (2010 Scheme) Short Note · 3 marks 10 Propofol 2017 February (2010 Scheme) Short Note · 3 marks 11 Halothane 2015 February (2010 Scheme) Short Note · 3 marks 12 Propofol. 2017 August (Supplementary) (2010 Scheme) Short Note · 3 marks 13 Halothane 2013 April (2010 Scheme) Short Note · 3 marks 14 Propofol 2014 September (Supplementary) (2010 Scheme) Short Note · 3 marks 15 Pre anesthetic medication 2018 July (Supplementary) (2010 Scheme) Short Note · 3 marks 16 Pre-anesthetic medication 2014 September (Supplementary) (2010 Scheme) Short Answer · 1 mark 17 Intravenous general anesthetics 2015 September (Supplementary) (2010 Scheme) Short Answer · 1 mark 18 Two intravenous and two inhalational anaesthetics 2013 September (Supplementary) (2010 Scheme) Short Answer · 1 mark 19 Pre- anesthetic medication 2017 August (Supplementary) (2010 Scheme) Short Answer · 1 mark 20 Ketamine 2021 December (Supplementary) (2010 Scheme) Short Answer · 1 mark 21 Pre anaesthetic medications 2024 March (Supplementary) (2010 Scheme) Short Answer · 0.3 marks 22 General anaesthetics used for induction 2022 July (Supplementary) (2019 Scheme) Short Answer · 0.2 marks