Paper II — 2022 May (Supplementary) (2010 Scheme) — Q6

Paper II

2022 May (Supplementary) (2010 Scheme) · 40 marks · 120 min

Question

Name four complications of Falciparum malaria.

Q62 marksShort Notes★✓

Answer

Four complications of falciparum malaria (driven largely by cytoadherence/sequestration of parasitized RBCs via PfEMP1):

1. Cerebral malaria — altered consciousness, seizures, coma.
2. Severe anaemia — from haemolysis and marrow suppression.
3. Acute kidney injury — including “blackwater fever” (massive intravascular haemolysis with haemoglobinuria).
4. Hypoglycaemia — from parasite glucose consumption and impaired hepatic gluconeogenesis.

(Other valid examples: ARDS; placental malaria; DIC and circulatory shock.)

Related Concepts

1. 1Malaria

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