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Paper II — 2015 February (2010 Scheme) — Q9

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Paper II
2015 February (2010 Scheme) · 40 marks · 120 min

Question

Mechanism of action of ciprofloxacin

Q91 marksShort Answers

Answer

Ciprofloxacin inhibits bacterial DNA gyrase (topoisomerase II) and topoisomerase IV, enzymes required for DNA supercoiling and replication. By blocking these enzymes, it prevents bacterial DNA synthesis, leading to bactericidal cell death.

  1. 1Quinolones

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  4. 4(2023 January (Supplementary) (2019 Scheme)Short Essay · 8 marks
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  14. 14A 24-year-old female with fever and chills came to causality. Gives history of urinary urgency and dysuria. Urine examination confirmed acute lower urinary tract infection and urine sample given for culture and sensitivity. (2023 July (Supplementary) (2010 Scheme)Essay · 6 marks
  15. 15Ciprofloxacin2024 March (Supplementary) (2019 Scheme)Short Answer · 4 marks
  16. 16Ciprofloxacin2013 April (2010 Scheme)Short Note · 3 marks
  17. 17Ciprofloxacin2024 August (Supplementary) (2010 Scheme)Short Note · 3 marks
  18. 18Ciprofloxacin2018 February (2010 Scheme)Short Note · 3 marks
  19. 19Treatment of multi drug resistance tuberculosis2018 July (Supplementary) (2010 Scheme)Short Note · 3 marks
  20. 20Gatifloxacin.2015 September (Supplementary) (2010 Scheme)Short Note · 3 marks
  21. 21Ofloxacin2021 May (Supplementary) (2010 Scheme)Short Note · 3 marks
  22. 22Non systemic antacids2016 October (Supplementary) (2010 Scheme)Short Note · 3 marks
  23. 23Ciprofloxacin2025 August (Supplementary) (2010 Scheme)Short Answer · 1 mark
  24. 24Ciprofloxacin2023 March (Supplementary) (2010 Scheme)Short Answer · 1 mark
  25. 25Fluoroquinolones2014 March (2010 Scheme)Short Answer · 1 mark
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  27. 27Assertion (A): Penicillin G is a broad-spectrum antibiotic. Reason (R): Broad-spectrum antibiotics are known to cause superinfections.2024 December (Supplementary) (2019 Scheme)MCQ · 1 mark
  28. 28Fluroquinolones.2025 March (Supplementary) (2010 Scheme)Short Answer · 1 mark
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