Paper I
2024 June (Supplementary) (2019 Scheme) · 100 marks · 180 min

Question

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  • (a) Discuss the management of cardiogenic shock. ( 4 mark(s)
  • (b) Discuss the treatment of status asthmaticus. 4 mark(s)
Q58 marksShort Essays

Answer

a) Management of cardiogenic shock

  • Identify and treat the underlying cause (revascularization for MI-related shock — primary PCI where possible).
  • Oxygen — corrects hypoxia.
  • Inotropic support: Dobutamine (beta-1 agonist, increases contractility with less peripheral vasoconstriction) or Dopamine (dose-dependent — D1 renal vasodilation at low dose, beta-1 inotropy at moderate dose, alpha-1 vasoconstriction at high dose).
  • Vasopressors (Norepinephrine) if hypotension is severe/refractory, to maintain organ perfusion pressure.
  • Cautious fluid management — fluids may worsen pulmonary congestion if the shock is due to pump failure rather than volume depletion; careful assessment of volume status is essential.
  • Mechanical circulatory support (intra-aortic balloon pump, ECMO) in refractory cases.

b) Treatment of status asthmaticus

  1. Oxygen — high-flow, titrated to maintain saturation.
  2. Nebulized SABA (Salbutamol), repeated/continuous, combined with nebulized Ipratropium — greater bronchodilation than either alone.
  3. Systemic corticosteroids, given early (IV Hydrocortisone/oral Prednisolone) — interrupts the attack despite delayed onset.
  4. IV Magnesium sulfate — add-on for severe attacks not responding adequately.
  5. IV Aminophylline — further-line addition in refractory cases.
  6. Mechanical ventilation — for impending/actual respiratory failure.

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