Paper II
2025 August (Supplementary) (2010 Scheme)
Question
Propylthiouracil
Q121 marksShort Answers
Answer
Uses: Hyperthyroidism/Graves’ disease (particularly preferred in pregnancy, first trimester); Thyroid storm (additional peripheral T4-to-T3 conversion block)
Adverse effects: Hepatotoxicity (rare fulminant hepatic failure); Agranulocytosis
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