Paper II — 2017 August (Supplementary) (2010 Scheme) — Q11

Paper II

2017 August (Supplementary) (2010 Scheme) · 40 marks · 120 min

Question

Anti- thyroid drugs safe during pregnancy

Q111 marksShort Answers★✓

Answer

Propylthiouracil is the preferred antithyroid drug in pregnancy, particularly the first trimester (carbimazole/methimazole carry a small risk of aplasia cutis and choanal/oesophageal atresia). In later pregnancy, some guidelines favour switching back to carbimazole/methimazole due to propylthiouracil’s hepatotoxicity risk, but propylthiouracil remains standard for the first trimester.

Related Concepts

1. 1Thyroid Hormones and Antithyroid Drugs

Other Years Asked

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3. 3Classify Thyroid inhibitor drugs. Describe the mechanism of action, and adverse effects of carbimazole. Explain the role of iodides in hyperthyroidism. (2+2+2)2022 May (Supplementary) (2010 Scheme)Essay · 6 marks
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7. 7A 35 years old woman came with complaints of heat intolerance, retraction of upper eyelid and menstrual irregularities. Her T3 , T4 , FT4 & FT3 are elevated while TSH is suppressed. Answer the following:2015 February (2010 Scheme)Essay · 6 marks
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9. 9Pharmacotherapy of Thyrotoxic crisis (thyroid storm)2024 June (Supplementary) (2019 Scheme)Short Answer · 4 marks
10. 10Mechanism of action, uses and adverse effects of Radio active iodine.2025 March (Supplementary (SAY)) (2019 Scheme)Short Answer · 4 marks
11. 11Carbimazole2022 October (Supplementary) (2010 Scheme)Short Note · 3 marks
12. 12Radioactive Iodine2024 March (Supplementary) (2010 Scheme)Short Note · 3 marks
13. 13Anti thyroid drugs2014 September (Supplementary) (2010 Scheme)Short Note · 3 marks
14. 14Radioactive Iodine2021 May (Supplementary) (2010 Scheme)Short Note · 3 marks
15. 15Lugol’s Iodine is given for 10 days prior to thyroidectomy surgery for Grave’s disease.2023 July (Supplementary) (2010 Scheme)Short Answer · 1 mark
16. 16Anti-thyroid drugs2018 July (Supplementary) (2010 Scheme)Short Answer · 1 mark
17. 17Explain the use of propranolol in thyrotoxicosis.2018 February (2010 Scheme)Short Answer · 1 mark
18. 18Methimazole acts by:2024 December (Supplementary) (2019 Scheme)MCQ · 1 mark
19. 19Antithyroid drugs2013 April (2010 Scheme)Short Answer · 1 mark
20. 20Drug used in thyrotoxic crisis2014 March (2010 Scheme)Short Answer · 1 mark
21. 21Propylthiouracil2025 August (Supplementary) (2010 Scheme)Short Answer · 1 mark
22. 22Thyrotoxic crisis.2015 September (Supplementary) (2010 Scheme)Short Answer · 1 mark
23. 23Anti thyroid drugs2016 October (Supplementary) (2010 Scheme)Short Answer · 1 mark
24. 24Radioactive iodine2020 February (Supplementary) (2010 Scheme)Short Answer · 1 mark
25. 25Use of Propranolol in Thyrotoxic crisis.2024 March (Supplementary) (2010 Scheme)Short Answer · 1 mark
26. 26The preferred drug for her is:2024 December (Supplementary) (2019 Scheme)MCQ · 1 mark
27. 27 Carbimazole for treatment of Thyroid storm2024 August (Supplementary) (2010 Scheme)Short Answer · 0.3 marks
28. 28Antithyroid drugs2019 February (2010 Scheme)Short Answer · 0.3 marks