Paper II
2025 March (Supplementary (SAY)) (2019 Scheme) · 100 marks · 180 min

Question

The available vaccines are

  • a) Live attenuated
  • b) Killed vaccine
  • c) Cellular component
  • d) Toxoid
Qiv1.8 marksMCQs

Answer

- [x] c) Cellular component

Pneumococcal vaccines are component (subunit) vaccines, using purified capsular material rather than the whole organism: the Pneumococcal Conjugate Vaccine (PCV), covering the most common invasive serotypes, uses capsular polysaccharide conjugated to a carrier protein (converting the response to T-dependent, effective even in infants), while the Pneumococcal Polysaccharide Vaccine (PPSV23) uses plain capsular polysaccharide from 23 serotypes. Neither is a live attenuated vaccine, a whole killed-cell vaccine, or a toxoid vaccine (pneumococcal disease is capsule/invasion-driven, not primarily toxin-mediated in the manner that would call for a toxoid approach).

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