Paper I — 2023 March (Supplementary) (2010 Scheme) — Q8

Paper I

2023 March (Supplementary) (2010 Scheme) · 40 marks · 120 min

Question

Name four killed vaccines.

Q82 marksShort Notes★✓

Answer

Four examples of killed (inactivated) vaccines — containing a whole pathogen (or its components) that has been killed/inactivated, unable to replicate in the host, generally requiring multiple doses/boosters to achieve durable immunity:

1. Inactivated Polio Vaccine (IPV, Salk vaccine).
2. Whole-cell pertussis vaccine (wP) — as used in the traditional DPT combination.
3. Rabies vaccine (modern cell-culture-derived, e.g., human diploid cell vaccine).
4. Inactivated influenza vaccine.

(Other valid examples: hepatitis A vaccine, typhoid Vi polysaccharide/injectable typhoid vaccine, cholera killed whole-cell oral vaccine.)

Related Concepts

1. 1Vaccines and Immunoprophylaxis

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