Paper I — 2024 March (Supplementary) (2010 Scheme) — Q7

Paper I

2024 March (Supplementary) (2010 Scheme) · 40 marks · 120 min

Question

Advantages and disadvantages of intravenous route of drug administration

Q73 marksShort Notes★✓

Answer

Advantages: 100% bioavailability (no absorption barrier), most rapid onset of action — essential in emergencies; permits precise, titratable dosing; allows administration of large volumes and irritant/hypertonic solutions that would damage other tissues.

Disadvantages: irreversible once injected (cannot be recalled if an adverse reaction occurs); requires aseptic technique and trained personnel; risk of infection, thrombophlebitis, and extravasation injury; not suitable for oily or insoluble substances; higher cost and inconvenience compared to oral dosing; risk of fluid overload with large volumes.

Related Concepts

1. 1Introduction and Routes of Drug Administration

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