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Paper II — 2025 March (Supplementary (SAY)) (2019 Scheme) — Qiii

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Paper II
2025 March (Supplementary (SAY)) (2019 Scheme) · 100 marks · 180 min

Question

This bacterium escapes immune destruction due to

  • a) Inhibition of phagocystosis
  • c) Bile solubility
  • b) Production of cyclic AMP
  • d) Autolysis
Qiii1.8 marksMCQs

Answer

- [x] a) Inhibition of phagocytosis

Streptococcus pneumoniae’s polysaccharide capsule mediates immune escape by inhibiting phagocytosis — resisting engulfment and killing by host neutrophils/macrophages, allowing the organism to survive and proliferate despite an active host immune response. “Production of cyclic AMP” describes the mechanism of cholera toxin, unrelated to pneumococcal immune evasion; “bile solubility” is a laboratory identification characteristic of the organism (used diagnostically), not an immune-evasion mechanism; “autolysis” refers to the organism’s own autolytic enzyme activity (releasing pneumolysin), not a mechanism of escaping immune destruction.

  1. 1Bacterial Morphology and Physiology

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