Paper II — 2024 December (Supplementary) (2019 Scheme) — Qiii

Paper II

2024 December (Supplementary) (2019 Scheme) · 100 marks · 180 min

Question

The drug that inhibits bacterial protein synthesis, useful against Bacteroides fragilis and may cause pseudomembranous enterocolitis is:

• a) Gentamicin
• b) Clarithromycin
• c) Clindamycin
• d) Minocycline

Qiii1 marksMCQs★✓

Answer

Correct answer: c) Clindamycin

Clindamycin inhibits bacterial protein synthesis by binding the 50S ribosomal subunit, has reliable activity against the anaerobe Bacteroides fragilis, and is classically associated with pseudomembranous enterocolitis (C. difficile-associated colitis) — one of the drugs most strongly linked to this complication, from its disruption of normal anaerobic gut flora.

Related Concepts

1. 1Macrolides and Other Antibacterials

Other Years Asked

1. 1Enumerate macrolide antibiotics. Describe briefly its mechanism of action and mention four uses. Add a note on linezolid. (1+2+1+2=6)2013 April (2010 Scheme)Essay · 6 marks
2. 2Compare and contrast: erythromycin and azithromycin.2024 December (Supplementary) (2019 Scheme)Short Answer · 4 marks
3. 3Clarithromycin2019 February (2010 Scheme)Short Note · 3 marks
4. 4Linezolid2021 December (Supplementary) (2010 Scheme)Short Note · 3 marks
5. 5Vancomycin2022 October (Supplementary) (2010 Scheme)Short Note · 3 marks
6. 6Azithromycin2014 March (2010 Scheme)Short Note · 3 marks
7. 7Mycobacterium avium complex.2017 February (2010 Scheme)Short Answer · 1 mark
8. 8What are streptogramins and mention one use of it2016 October (Supplementary) (2010 Scheme)Short Answer · 1 mark
9. 9Mechanism of action of clarithromycin.2017 February (2010 Scheme)Short Answer · 1 mark
10. 10Used in anaerobic infections2018 July (Supplementary) (2010 Scheme)Short Answer · 1 mark
11. 11Clindamycin for mycoplasma pneumonia Name the following (Two examples for each): (8x1=8)2024 March (Supplementary) (2019 Scheme)Short Answer · 0.2 marks