Paper I
2024 December (Supplementary) (2019 Scheme) · 100 marks · 180 min

Question

The hypersensitivity reaction associated with this condition is

  • a) Type-I
  • b) Type-II
  • c) Type-III
  • d) Type-IV
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Answer

Correct answer: a) Type-I

This clinical picture (acute breathlessness, facial/lip swelling, watering eyes/nose, minutes after a bee sting) is anaphylaxis — a systemic Type I (IgE-mediated, immediate) hypersensitivity reaction, triggered by mast cell/basophil degranulation upon re-exposure to bee venom allergen cross-linking pre-bound IgE.

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