Paper I — 2024 December (Supplementary) (2019 Scheme) — Qxviii

Paper I

2024 December (Supplementary) (2019 Scheme) · 100 marks · 180 min

Question

Which of the following cytokine is NOT secreted by TH2 cells

• a) IL-4
• b) IL-5
• c) IFN-Gamma
• d) IL-13

Qxviii1 marksMCQs★✓

Answer

Correct answer: c) IFN-Gamma

IFN-gamma is the signature cytokine of Th1 cells, not Th2 cells. Th2 cells (relevant to Type I hypersensitivity reactions like this bee-sting anaphylaxis) characteristically secrete IL-4, IL-5, and IL-13, which drive IgE class-switching (IL-4/IL-13), eosinophil activation (IL-5), and the allergic/anti-parasitic immune response.

Related Concepts

1. 1Type I Hypersensitivity

Other Years Asked

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4. 4Which of the following immunoglobulins play a major role in this reaction2024 December (Supplementary) (2019 Scheme)MCQ · 1 mark
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