Paper I — 2024 December (Supplementary) (2019 Scheme) — Qxvii

Paper I

2024 December (Supplementary) (2019 Scheme) · 100 marks · 180 min

Question

Release of which of the following chemical mediators is most likely responsible for this finding

• a) Nitric oxide
• b) Prostaglandin E2
• c) Complement C3b
• d) Histamine

Qxvii1 marksMCQs★✓

Answer

Correct answer: d) Histamine

Histamine, released from mast cell degranulation in this Type I hypersensitivity reaction, is the principal mediator responsible for the acute vasodilatation and increased vascular permeability producing the facial/lip swelling (angioedema) and rhinorrhoea/watering eyes described in this bee-sting anaphylaxis scenario.

Related Concepts

1. 1Type I Hypersensitivity

Other Years Asked

1. 1Type 1 Hypersensitivity reaction2022 July (Supplementary) (2019 Scheme)Short Answer · 4 marks
2. 2Type-I hyper sensitivity reaction.2023 January (Supplementary) (2019 Scheme)Short Answer · 4 marks
3. 3Which of the following immunoglobulins play a major role in this reaction2024 December (Supplementary) (2019 Scheme)MCQ · 1 mark
4. 4Type I hypersensitivity reaction mediated by ------------------- antibody2024 March (Supplementary) (2019 Scheme)1 mark
5. 5The hypersensitivity reaction associated with this condition is2024 December (Supplementary) (2019 Scheme)MCQ · 1 mark
6. 6Which of the following cytokine is NOT secreted by TH2 cells2024 December (Supplementary) (2019 Scheme)MCQ · 1 mark