Paper I
2022 July (Supplementary) (2019 Scheme) · 100 marks · 180 min

Question

Describe the major Hospital Acquired Infections (HAI) types. Add a note on standard precautions (4+4)

Q48 marksShort Essays

Answer

Major types of Hospital-Acquired Infections (HAI):

  1. Catheter-Associated Urinary Tract Infection (CAUTI) — the most common HAI in many settings, associated with indwelling urinary catheters; commonly E. coli, Klebsiella, Pseudomonas.
  2. Surgical Site Infection (SSI) — infection at or near a surgical incision within a defined post-operative period; commonly S. aureus (including MRSA), coagulase-negative staphylococci.
  3. Central Line-Associated Bloodstream Infection (CLABSI) — associated with intravascular catheters; commonly coagulase-negative staphylococci, S. aureus, Candida.
  4. Ventilator-Associated Pneumonia (VAP) — pneumonia developing in mechanically ventilated patients; commonly Pseudomonas aeruginosa, Acinetobacter, Klebsiella.
  5. Clostridium difficile-associated diarrhoea — following antibiotic-disrupted normal gut flora.

Risk factors: invasive devices, prolonged hospital stay, immunosuppression, extremes of age, broad-spectrum antibiotic use, surgical procedures.

Note on standard precautions Standard precautions are a set of infection-control practices applied to all patients regardless of known/suspected infection status, since any patient may harbour a transmissible pathogen:

  • Hand hygiene — the single most important and cost-effective measure, before/after every patient contact.
  • Personal Protective Equipment (PPE) — gloves, gowns, masks, eye protection, used based on anticipated exposure to blood/body fluids.
  • Safe injection practices — single-use needles/syringes, safe sharps disposal.
  • Respiratory hygiene/cough etiquette.
  • Environmental cleaning and disinfection of surfaces/equipment.
  • Safe handling and disposal of biomedical waste, including sharps.
  • Appropriate patient placement/isolation when transmission-based precautions (contact, droplet, airborne) are additionally required for specific known/suspected infections, building on the foundation of standard precautions applied universally.

Significance: consistent application of standard precautions, combined with antibiotic stewardship and device-minimization strategies, forms the core of hospital infection-prevention programmes, given the significant morbidity, mortality, and cost associated with HAIs.

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