Paper II — 2024 December (Supplementary) (2019 Scheme) — Qxiv

Paper II

2024 December (Supplementary) (2019 Scheme) · 100 marks · 180 min

Question

(A) Intravesical administration of BCG (Bacillus Calmette Geurin) is a treatment for bladder carcinoma (R) BCG elicits granulomatous inflammation and local anti tumour immune response.

• a) Both A & R are correct and R is the reason for A
• b) Both A & R are correct but R is not reason for A
• c) A is correct R is incorrect
• d) A is incorrect R is correct

Qxiv1 marksMCQs★✓

Answer

Correct answer: a) Both A & R are correct and R is the reason for A

Both statements are correct, and R explains A. Intravesical BCG instillation is standard treatment for high-risk non-muscle-invasive (superficial) bladder carcinoma. It works by inducing a local granulomatous inflammatory reaction in the bladder wall, which recruits and activates immune effector cells (macrophages, cytotoxic T cells, NK cells) that mount an anti-tumour immune response — directly explaining its therapeutic effect described in A.

Related Concepts

1. 1Chronic and Granulomatous Inflammation

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