Paper I
2024 December (Supplementary) (2019 Scheme) · 100 marks · 180 min

Question

A fact NOT pathognomonic of visceral Leishmaniasis is

  1. Trypomastigotes in bone marrow
  2. LD bodies in bone marrow
  3. Amastigotes in skin smears
  4. Trypomastigotes in peripheral blood a) 1, 2, 3 are correct b) 2, 3, 4 are correct c) 1, 3, 4 are correct d) 1, 2, 4 are correct
  • a) 1, 2, 3 are correct
  • b) 2, 3, 4 are correct
  • c) 1, 3, 4 are correct
  • d) 1, 2, 4 are correct
Qviii1 marksMCQs

Answer

Classical clinical/laboratory features of visceral leishmaniasis (kala-azar), caused by Leishmania donovani and transmitted by sandfly bite, include: prolonged/irregular fever, progressive hepatosplenomegaly (splenomegaly typically more prominent), pancytopenia (anaemia, leukopenia, thrombocytopenia), hyperpigmentation of the skin (the literal meaning of “kala-azar”), weight loss/wasting, and demonstration of LD (Leishman-Donovan) bodies in splenic/bone marrow aspirate. Features that would NOT be considered pathognomonic/classical of visceral leishmaniasis include findings more typical of other conditions — e.g., a “strawberry cervix” (trichomoniasis), rice-water stool (cholera), or a butterfly (malar) rash (SLE) — any such non-specific or unrelated finding would be the “fact NOT pathognomonic” the question is asking to identify. Without the original four numbered statements from the source question, the specific combination intended by the examiner cannot be confirmed.

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