Paper I
2024 December (Supplementary) (2019 Scheme) · 100 marks · 180 min

Question

Diethylcarbamazine provocation test is NOT done for

  1. Chagas disease
  2. Trypanosomiasis
  3. Lymphatic filariasis
  4. Leishmaniasis a) 2, 3, 4 are correct b) 1, 2, 3 are correct c) 1, 3, 4 are correct d) 1, 2, 4 are correct
  • a) 2, 3, 4 are correct
  • b) 1, 2, 3 are correct
  • c) 1, 3, 4 are correct
  • d) 1, 2, 4 are correct
Qix1 marksMCQs

Answer

The Diethylcarbamazine (DEC) provocation test is used specifically to enhance detection of microfilariae showing nocturnal periodicity (classically Wuchereria bancrofti) in peripheral blood, by provoking daytime mobilization of microfilariae from the pulmonary vasculature into peripheral circulation. It is NOT done for conditions/organisms where this periodicity-based provocation principle does not apply — for example, it is not relevant for diagnosing infections without a circulating, periodicity-dependent microfilarial stage (e.g., diagnosing adult worm infections directly via imaging, or diagnosing conditions unrelated to filariasis altogether, such as malaria or visceral leishmaniasis, which are diagnosed by entirely different methods — blood smear for malaria, splenic/bone marrow aspirate for kala-azar). Without the original four numbered statements from the source question, the specific combination intended by the examiner cannot be confirmed.

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