Question
Adverse effects of glucocorticoids
Q63 marksShort Notes
Answer
- Cushingoid features (moon facies, buffalo hump, central obesity)
- Osteoporosis and increased fracture risk
- Hyperglycaemia/precipitation of diabetes
- Hypertension and fluid retention
- Increased susceptibility to infections (immunosuppression)
- Peptic ulceration
- Muscle wasting/myopathy
- Skin thinning, poor wound healing, easy bruising
- Adrenal suppression (HPA axis) — risk with abrupt withdrawal
- Cataract and glaucoma (long-term)
- Psychiatric disturbances (mood changes, insomnia)
- 1Corticosteroids
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