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Paper II — 2022 February (2019 Scheme) — Q5

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Paper II
2022 February (2019 Scheme) · 100 marks · 180 min

Question

Describe the therapeutic uses and adverse effects of Corticosteroids. (4+4)

Q58 marksShort Essays

Answer

Therapeutic uses of corticosteroids

  • Replacement therapy — Addison’s disease
  • Anti-inflammatory/immunosuppressive use — rheumatoid arthritis, SLE, and other autoimmune/inflammatory disease
  • Allergic emergencies — anaphylaxis, angioedema, severe asthma exacerbation
  • Organ transplant rejection prophylaxis
  • Cerebral edema (raised intracranial pressure from tumours)
  • Nephrotic syndrome
  • Antenatal corticosteroids for fetal lung maturation in threatened preterm labour

Adverse effects

  • Cushingoid features (moon face, central obesity, striae)
  • Hyperglycemia
  • Osteoporosis
  • Peptic ulceration
  • Increased susceptibility to infection
  • Hypertension
  • Growth retardation in children
  • Cataract/glaucoma
  • Adrenal suppression (HPA axis) — risk of adrenal crisis on abrupt withdrawal
  • Psychiatric disturbances
  • Myopathy
  1. 1Corticosteroids

Other Years Asked

  1. 1day2025 March (Supplementary (SAY)) (2019 Scheme)Essay · 10 marks
  2. 2Glucocorticosteroids2024 June (Supplementary) (2019 Scheme)Short Essay · 8 marks
  3. 3Corticosteroids.2022 July (Supplementary) (2019 Scheme)Short Essay · 8 marks
  4. 4Classify corticosteroids. Describe the uses and adverse effects of glucocorticoids (2+2+2)2019 February (2010 Scheme)Essay · 6 marks
  5. 5Enumerate Four glucocorticoids. Explain the measures to minimize hypothalamo pituitary adrenal axis suppression. Discuss two other adverse drug reactions of glucocorticoid therapy. (2+3+1)2024 December (Supplementary) (2019 Scheme)Short Essay · 6 marks
  6. 6A 60 year old lady is suffering from rheumatoid arthritis and has been prescribed prednisolone. Answer the following:2013 April (2010 Scheme)Essay · 6 marks
  7. 7Explain the adverse effects and role of inhaled steroids in Bronchial asthma.2025 March (Supplementary (SAY)) (2019 Scheme)Short Answer · 4 marks
  8. 8Adverse effects of glucocorticoids2018 July (Supplementary) (2010 Scheme)Short Note · 3 marks
  9. 9Therapeutic uses of Corticosteroids2024 August (Supplementary) (2010 Scheme)Short Note · 3 marks
  10. 10Inhaled corticosteroids2020 February (Supplementary) (2010 Scheme)Short Note · 3 marks
  11. 11Adverse effects of Corticosteroids2025 August (Supplementary) (2010 Scheme)Short Note · 3 marks
  12. 12Therapeutic uses of corticosteroids2023 July (Supplementary) (2010 Scheme)Short Note · 3 marks
  13. 13Mechanism of action of hydrocortisone2016 October (Supplementary) (2010 Scheme)Short Answer · 1 mark
  14. 14Prednisolone.2025 March (Supplementary) (2010 Scheme)Short Answer · 1 mark
  15. 15Prednisolone2022 October (Supplementary) (2010 Scheme)Short Answer · 1 mark
  16. 16Drugs used in inflammatory bowel disease2023 July (Supplementary) (2010 Scheme)Short Answer · 0.3 marks
  17. 17Drugs for psoriasis2019 July (Supplementary) (2010 Scheme)Short Answer · 0.3 marks
  18. 18Drugs acting through nuclear receptors2023 March (Supplementary) (2010 Scheme)Short Answer · 0.3 marks
  19. 19Drugs used in Psoriasis2023 March (Supplementary) (2010 Scheme)Short Answer · 0.3 marks

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