Paper II — 2025 March (Supplementary (SAY)) (2019 Scheme) — Qv

Paper II

2025 March (Supplementary (SAY)) (2019 Scheme) · 100 marks · 180 min

Question

Drug of choice for treatment in this patient is

• a) Cefuroxime
• b) Ceftriaxone
• c) Ceftazidime
• d) Cefoxitin

Qv1.8 marksMCQs★✓

Answer

- [x] b) Ceftriaxone

A third-generation cephalosporin (ceftriaxone or cefotaxime) forms the backbone of empirical/definitive antibiotic therapy for bacterial meningitis, including pneumococcal meningitis, with vancomycin added where resistant pneumococcal strains are a concern. Cefuroxime (a second-generation cephalosporin) has inferior CNS penetration and narrower coverage; ceftazidime and cefoxitin are not standard choices for pneumococcal meningitis (ceftazidime has relatively weaker Gram-positive/pneumococcal activity and is more commonly reserved for Pseudomonas coverage; cefoxitin is a cephamycin used mainly for anaerobic/mixed infections, not meningitis).

Related Concepts

1. 1Antimicrobial Agents and Antimicrobial Resistance

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