Paper I — 2022 May (Supplementary) (2010 Scheme) — Q8

Paper I

2022 May (Supplementary) (2010 Scheme) · 40 marks · 120 min

Question

List two bactericidal and two bacteriostatic anti tubercular drugs

Q82 marksShort Notes★✓

Answer

Two bactericidal anti-tubercular drugs: Isoniazid (highly bactericidal, especially against rapidly dividing extracellular organisms) and Rifampicin (bactericidal against both actively dividing and semi-dormant/slowly metabolizing organisms — its sterilizing activity is a key reason for the shortened modern short-course regimen).

Two bacteriostatic anti-tubercular drugs: Ethambutol and Para-aminosalicylic acid (PAS) — both primarily inhibit bacterial growth rather than directly killing the organism.

(Note: Pyrazinamide and Streptomycin are also bactericidal, the former particularly active against semi-dormant intracellular organisms in an acidic environment; Ethionamide is another bacteriostatic second-line agent.)

Related Concepts

1. 1Antimicrobial Agents and Antimicrobial Resistance

Other Years Asked

1. 12025 March (Supplementary (SAY)) (2019 Scheme)Short Answer · 10 marks
2. 2Classification of antibiotics based on the mechanism of action2023 July (Supplementary) (2010 Scheme)Short Essay · 5 marks
3. 3Write FOUR mechanisms of antimicrobial resistance in bacteria with examples.2024 March (Supplementary) (2019 Scheme)Short Answer · 4 marks
4. 4Name four mechanisms of antimicrobial resistance in bacteria.2023 July (Supplementary) (2019 Scheme)Short Answer · 4 marks
5. 5Name TWO cell wall acting antibiotics2024 March (Supplementary) (2010 Scheme)Short Note · 2 marks
6. 6Plasmid and it’s importance in drug resistance.2020 February (Supplementary) (2010 Scheme)Short Note · 2 marks
7. 7Extended spectrum beta lactamases2017 August (Supplementary) (2010 Scheme)Short Note · 2 marks
8. 8Drug of choice for treatment in this patient is2025 March (Supplementary (SAY)) (2019 Scheme)MCQ · 1.8 marks
9. 9Name two narrow spectrum antibiotics.2023 January (Supplementary) (2019 Scheme)1 mark
10. 10Name two antibiotics inhibiting bacterial cell wall synthesis2023 July (Supplementary) (2019 Scheme)1 mark
11. 11Gram negative bacteria are inherently resistant to2024 December (Supplementary) (2019 Scheme)MCQ · 1 mark