Paper I — 2025 March (Supplementary (SAY)) (2019 Scheme) — Qiii

Paper I

2025 March (Supplementary (SAY)) (2019 Scheme) · 100 marks · 180 min

Question

The medication preferred in the treatment of drug-induced parkinsonism is

• a) Ropinirole
• b) Carbidopa
• c) Selegiline
• d) Trihexyphenidyl

Qiii1 marksMCQs★✓

Answer

Correct answer: d) Trihexyphenidyl

Drug-induced parkinsonism results from dopamine D2 receptor blockade (typically antipsychotics), not dopamine deficiency, so restoring the dopamine-acetylcholine balance with a centrally acting antimuscarinic (trihexyphenidyl) directly addresses the mechanism. Dopaminergic drugs (ropinirole, a dopamine agonist; selegiline, an MAO-B inhibitor) would be ineffective, since the problem is blocked receptors, not insufficient dopamine, and could antagonize the causative antipsychotic’s therapeutic effect.

Related Concepts

1. 1Antiparkinsonian Drugs

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