Question
COMT inhibitor
Q18 0.3 marks Short Answers ★ ✓
Answer
Entacapone — inhibits catechol-O-methyltransferase (COMT), the peripheral enzyme that degrades levodopa, thereby increasing levodopa’s plasma half-life and bioavailability when used as an adjunct in Parkinson’s disease therapy.
1 Antiparkinsonian Drugs
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