Paper I — 2022 May (Supplementary) (2010 Scheme) — Q16

Paper I

2022 May (Supplementary) (2010 Scheme) · 40 marks · 120 min

Question

Peripheral decarboxylase inhibitor

Q160.3 marksShort Answers★✓

Answer

Carbidopa, Benserazide — both combined with levodopa in Parkinson’s disease treatment to prevent peripheral decarboxylation of levodopa to dopamine, reducing peripheral adverse effects (nausea, hypotension) and allowing more levodopa to reach the CNS.

Related Concepts

1. 1Antiparkinsonian Drugs

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