Question
Mention adverse effects of Aminoglycosides
Q94 marksShort Answers
Answer
- Nephrotoxicity — reversible, from proximal tubular accumulation of the drug.
- Ototoxicity — often irreversible, vestibular and/or cochlear damage; risk increases with prolonged use, high doses, and concurrent loop diuretics.
- Neuromuscular blockade — at high doses, can potentiate/mimic non-depolarizing muscle relaxants, particularly relevant peri-operatively.
- Hypersensitivity reactions — less common than with beta-lactams, but can occur.
- 1Aminoglycosides
Other Years Asked
- 1Mention two aminoglycosides. Explain four common properties of aminoglycosides. What is post-antibiotic
effect. (1+4+1)2024 December (Supplementary) (2019 Scheme)Short Essay · 6 marks
- 2Write in detail on the mechanism of action, uses, and adverse effects of aminoglycoside antibiotics.2025 March (Supplementary (SAY)) (2019 Scheme)Short Essay · 6 marks
- 3List aminoglycoside antibiotics. Mention its four common properties and two adverse effects.2015 September (Supplementary) (2010 Scheme)Essay · 6 marks
- 4Adverse effects of aminoglycosides2014 September (Supplementary) (2010 Scheme)Short Note · 3 marks
- 5Aminoglycosides2025 August (Supplementary) (2010 Scheme)Short Note · 3 marks
- 6Adverse effects of aminoglycoside antibiotics2016 February (2010 Scheme)Short Note · 3 marks
- 7Antibiotics given only parenterally2016 October (Supplementary) (2010 Scheme)Short Answer · 1 mark
- 8Aminoglycoside antibiotics.2025 March (Supplementary) (2010 Scheme)Short Answer · 0.3 marks
