Paper I
2023 July (Supplementary) (2010 Scheme) · 40 marks · 120 min
Question
Name any two antigen-antibody reactions.
Q92 marksShort Notes
Answer
Two examples of antigen-antibody reactions:
- Agglutination — clumping of a particulate antigen (whole cells, or antigen adsorbed onto a carrier particle) when it reacts with specific antibody, cross-linking particles into visible aggregates (e.g., Widal test, blood grouping).
- Precipitation — formation of a visible insoluble complex when a soluble antigen reacts with specific antibody in optimal proportions (e.g., Elek’s gel precipitation test, VDRL flocculation test).
(Other valid examples: complement fixation, neutralization, immunofluorescence, ELISA.)
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